中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (48): 9015-9019.doi: 10.3969/j.issn.2095-4344.2012.48.016

• 骨与关节循证医学 evidence-based medicine of the bone and joint • 上一篇    下一篇

内侧胫骨平台倾斜角与前交叉韧带损伤相关性的Meta分析

曾 超1，魏 捷2，高曙光1，雷光华1，朱鹤远1，张 凯1   

  1. 1中南大学湘雅医院骨科，湖南省长沙市 410008
    2中南大学公共卫生学院，湖南省长沙市 410008
  • 收稿日期:2012-01-18 修回日期:2012-03-08 出版日期:2012-11-25 发布日期:2012-11-25
  • 通讯作者: 雷光华，博士后，教授，博士生导师，中南大学湘雅医院骨科，湖南省长沙市 410008 lgh9640@sina.com
  • 作者简介:曾超★，男，1988年生，湖南省长沙市人，汉族，中南大学在读硕士，主要从事人工关节与微创外科的研究。 125562108@qq.com

Meta-analysis on the association between medial tibial plateau slope angle and anterior cruciate ligament injuries

Zeng Chao1, Wei Jie2, Gao Shu-guang1, Lei Guang-hua1, Zhu He-yuan1, Zhang Kai1   

  1. 1Department of Orthopedics, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China
    2School of Public Health of Central South University, Changsha 410008, Hunan Province, China
  • Received:2012-01-18 Revised:2012-03-08 Online:2012-11-25 Published:2012-11-25
  • Contact: Lei Guang-hua, Doctor, Professor, Doctoral supervisor, Department of Orthopedics, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China Lgh9640@sina.com
  • About author:Zeng Chao★, Studying for master’s degree, Department of Orthopedics, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China 125562108@qq.com

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被引次数

4

摘要：

背景：内侧胫骨平台倾斜角作为前交叉韧带损伤的一项解剖学相关危险因素，一直受到研究者的重视，但其相关性的存在与否，各项研究的结果不尽相同。
目的：分析内侧胫骨平台倾斜角与前交叉韧带损伤的相关性，并探讨其是否存在性别特异性。
方法：计算机检索cochrane图书馆、MEDLINE数据库、Elsevier数据库、中国生物医学文献数据库、万方数据库以及手工检索相关文献的参考文献。所有检索截止至2011-11-01。收集国内外公开发表的有关内侧胫骨平台倾斜角与前交叉韧带损伤相关性的病例对照研究和横断面研究文献，采用STATA 11.0统计软件进行统计分析。
结果与结论：纳入Meta分析的文献共12篇，累计研究对象1 823例，损伤组888例，对照组925例。纳入研究表明，损伤组与对照组内侧胫骨平台倾斜角的合并加权均值差为1.06，95%CI(0.36，1.76)，P < 0.05；亚组分析结果表明，男性病例中损伤组与对照组内侧胫骨平台倾斜角的合并加权均值差为0.84，95%CI(-0.03，1.70)，P > 0.05，女性病例中损伤组与对照组内侧胫骨平台倾斜角的合并加权均值差(WMD)为1.62，95%CI(0.72，2.52)，P < 0.05。提

关键词: 前交叉韧带, 胫骨平台倾斜, 胫骨后倾斜, Meta分析

Abstract:

BACKGROUND: As an anatomy associated risk factors of the anterior cruciate ligament injury, medial tibial plateau slope angle has been attracted much more attention, but as for the correlation between the anterior cruciate ligament injury and medial tibial plateau slope angle presence or absence, the results of the studies are not the same.
OBJECTIVE: To determine the association between medial tibial plateau slope angle and anterior cruciate ligament injuries, and to investigate gender differences between anterior cruciate ligaments injured subjects and gender-matched controls.
METHODS: The Cochrane library, Medline database, Elsevier database, Chinese Biomedical database and Wanfang database were retrieved by computer and the hand research of relevant literatures was performed. The deadline of all the retrieves was 2011-11-01. We included case-control and sectional studies on the association between medial tibial plateau slope angle and anterior cruciate ligament injury. The STATA11.0 software package was used for data-analysis.
RESULTS AND CONCLUSION: Twelve trails with 1 823 objects were included for Meta analysis (888 objects in injury group and 925 objects in control group). For the whole objects in the injury group and control group, the pooled weighted mean difference for medial tibial plateau slope angle was 1.06, 95% confidence interval (CI) (0.36, 1.76), and P < 0.05. Subgroup analysis showed that, for the male objects, the pooled weighted mean difference for medial tibial plateau slope angle in the injury group and the control group was 0.84,95%CI:(-0.03,1.70) and P > 0.05. For the female objects, the pooled weighted mean difference for medial tibial plateau slope angle was 1.62, 95%CI (0.72, 2.52) and P < 0.05. The results of this Meta-analysis suggest that increased medial tibial plateau slope appears to contribute to anterior cruciate ligament injuries in females, but not in males.

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