中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (47): 8835-8841.doi: 10.3969/j.issn.2095-4344.2012.47.021

• 生物材料基础实验 basic experiments of biomaterials • 上一篇    下一篇

亲水性纤维含银敷料覆盖肛瘘术后创面的作用

杨 旭1,周惠芬2,张苏闽2,王元钊1,叶 妮1,王 轶1,赵 璟1   

  1. 1南京市中西医结合医院肛肠科,江苏省南京市 210014
    2南京市中医院全国肛肠病医疗中心,江苏省南京市 210000
  • 收稿日期:2012-07-21 修回日期:2012-08-13 出版日期:2012-11-18 发布日期:2012-11-18
  • 通讯作者: 王元钊,副主任医师,南京市中西医结合医院肛肠科,江苏省南京市 210014
  • 作者简介:杨旭★,男,1985年生,安徽省六安市人,汉族,2011年南京中医药大学研究生院毕业,硕士,医师,主要从事肛肠疾病的中西医结合疗法研究。 并列第一作者:周惠芬★,女,1984年生,江苏省南京市人,汉族,南京中医药大学毕业,硕士,医师,主要从事肛肠疾病的外治疗法研究。

HydrofiberTM dressing with silver in wound healing after surgery for anal fistula

Yang Xu1, Zhou Hui-fen2, Zhang Su-min2, Wang Yuan-zhao1, Ye Ni1, Wang Yi1, Zhao Jing1   

  1. 1Department of Anorectal Surgery, Nanjing Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing 210014, Jiangsu Province, China
    2National Medical Center of Anorectal Diseases, Nanjing Hospital of Traditional Chinese Medicine, Nanjing 210000, Jiangsu Province, China
  • Received:2012-07-21 Revised:2012-08-13 Online:2012-11-18 Published:2012-11-18
  • Contact: Wang Yuan-zhao, Associate chief physician, Department of Anorectal Surgery, Nanjing Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing 210014, Jiangsu Province, China
  • About author:Yang Xu★, Master, Physician, Department of Anorectal Surgery, Nanjing Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing 210014, Jiangsu Province, China 15996213064@163.com Zhou Hui-fen★, Master, Physician, National Medical Center of Anorectal Diseases, Nanjing Hospital of Traditional Chinese Medicine, Nanjing 210000, Jiangsu Province, China Yang Xu and Zhou Hui-fen contributed equally to this paper.

摘要:

背景:亲水性纤维含银敷料在其他创面治疗中目前已取得较多临床证据,但其
对肛瘘患者术后创面康复的作用研究较少。
目的:观察亲水性纤维含银敷料覆盖对肛瘘患者术后创面康复的作用。
方法:将57例肛瘘术后患者随机分为试验组29例和对照组28例,试验组在术后给予亲水性纤维含银敷料换药,3 d 1次,对照组术后给予无菌凡士林纱布换药,1次/d,观察两组患者的首次换药创面疼痛程度、渗液明显减少时间、换药次数、创面康复时间及换药费用等指标。
结果与结论:试验组首次换药时创面疼痛程度明显轻于对照组(P < 0.05),渗液明显减少时间、换药次数、创面康复时间明显少于对照组(P < 0.05);但试验组换药费用明显高于对照组(P < 0.05)。表明亲水性纤维含银敷料覆盖于肛瘘患者术后创面可减少刺激,明显减轻疼痛,提供湿性修复环境,加速创面愈合,减少换药次数,提高患者满意度。

关键词: 亲水性纤维含银敷料, 肛瘘, 创面康复, 覆盖, 疼痛程度, 创面愈合, 生物材料, 凡士林纱布, 换药次数

Abstract:

BACKGROUND: Much clinical evidence have proved the effect of HydrofiberTM dressing with silver in other wounds healing, but the reports on the effect of HydrofiberTM dressing with silver in wounds healing after surgery for anal fistula are rare.
OBJECTIVE: To observe the therapeutic efficacy of HydrofiberTM dressing with silver in wounds healing after surgery of anal fistula.
METHODS: Fifty-seven patients with anal fistula surgery were randomly divided into treatment group (n=29, HydrofiberTM dressing with silver, once every 3 days) and the control group (n=28, Vaseline gauze, once per day). The level of wound pain during treatment, wound exudates situations, the frequency of dressing changes, the healing time and the cost of dressing changes were observed and compared.
RESULTS AND CONCLUSION: The wound pain level during treatment, wound exudates situations, the healing time and the frequency of dressing changes in treatment group were all significantly less than those in the control group (P < 0.05), but the cost of dressing changes in the experimental group was significantly higher than that in the control group (P < 0.05). HydrofiberTM dressing with silver for wounds healing after anal fistula surgery can obviously reduce the wound pain level during treatment, provide moist repair environment, accelerate wound healing, reduce the frequency of dressing changes and improve patient satisfaction.

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