| [1] Fan Z,Wang J,Wang Z,et al.One-pot synthesis of graphene/ hydroxyapatite nanorod composite for tissue engineering. Carbon. 2014;66(1):407-416.[2] Novoselov KS,Geim AK,Morozov SV,et al.Electric field effect inatomically thin carbon films. Science. 2004;306(5696):666-669.[3] Lee C,Wei X,Kysar JW,et al．Measurement of the elastic properties and intrinsic strength of monolayer grapheme. Science. 2008;321(5887):385-388．[4] Balandin AA,Ghosh S,Bao W,et al.Superior thermal conductivityof single-layer grapheme.Nano Lett. 2008;8(3):902-907．[5] Zhang B,Wang Y,Zhai G,et al.Biomedical applications of thegraphene- based materials.Mater Sci Eng C. 2016;61(8): 953-964.[6] Holt BD,Wright ZM,Arnold AM,et al.Graphene oxide as a scaffold for bone regeneration. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017;9(3).doi:10.1002/wnan.1437. Epub 2016 Oct 26.[7] Jafari M,Paknejad Z,Rad MR,et al.Polymeric scaffolds in tissue engineering: a literature review. J Biomed Mater Res B Appl Biomater. 2017;105(2):431-459.[8] Gong T,Xie J,Liao J,et al.Nanomaterials and bone regeneration. Bone Res.2015;3(3):123-129.[9] 吕成奇,邹德荣.石墨烯材料在组织工程方面应用的新进展[J].口腔医学,2014,34(4):304-306.[10] Zhang Y,Ali SF,Dervishi E,et al. Cytotoxicity effects of graphene and single-wall carbon nanotubes in neural phaeochromocytoma- derived PC12 cells.Acs Nano. 2010;4(6):3181-3186.[11] Kalbacova M,Broz A,Kong J,et al.Graphene substrates promoteadherence of human osteoblasts and mesenchymal stromal cells.Carbon.2010;48(15):4323-4329.[12] 徐宏杨,范敏敏,张志荣,等.氧化石墨烯PEG化后对L929细胞毒性的影响[J].华西药学杂志,2015, 30(4):425-427.[13] Liao KH,Lin YS,Macosko CW,et al.Cytotoxicity of graphene oxide and graphene in human erythrocytes and skin fibroblastsACS Appl Mater Interfaces.2011;3(7):2607-2615.[14] 赵梦,温朝辉.石墨烯及其复合材料在组织工程领域的研究进展[J].医学研究杂志,2017,46(12):175-178.[15] Bengtson S,Kling K,Madsen AM,et al.No cytotoxicity or genotoxicity of graphene and graphene oxide in murine lung epithelial FE1 cells in vitro. Environ Mol Mutagen. 2016;57(6): 469-476.[16] Girish CM,Sasidharan A,Gowd GS,et al.Confocal Raman imaging study showing macrophage mediated biodegradation of graphene in vivo.Adv Healthc Mater.2013;2(11):1489-1500.[17] Schinwald A,Murphy F,Askounis A,et al.Minimal oxidation and inflammogenicity of pristine graphene with residence in the lung. Nanotoxicology.2014;8(8):824-832．[18] Jin L,Lee JH,Jin OS,et al.Stimulated osteogenic differentiation of human mesenchymal stem cells by reduced graphene oxide.J Nanosci Nanotechnol.2015;15(10):7966-7970.[19] Kang ES,Kim DS,Suhito IR,et al.Guiding osteogenesis of mesenchymal stem cells using carbon-based nanomaterials. Nano Convergence.2017;4(1):1-14.[20] Han X,Chua M,Islam I,et al.CVD-grown monolayer graphene induces osteogenic but not odontoblastic differentiation of dental pulp stem cells.Dent Mater.2016;33(1):13-21.[21] Crowder SW,Prasai D,Rath R,et al.Three-dimensional graphene foams promote osteogenic differentiation of humanmesenchymal stem cells. Nanoscale. 2013;5(10):4171-4176.[22] Lee WC,Lim CH,Shi H,et al.Origin of enhanced stem cell growth and differentiation on graphene and graphene oxide. Acs Nano. 2011;5(9):7334-7341.[23] Aryaei A,Jayatissa AH,Jayasuriya AC,et al.The effect of graphene substrate on osteoblast cell adhesion and proliferation. J Biomed Mater Res A.2014;102(9):3282-3290.[24] Elkhenany H,Amelse L,Lafont A,et al.Graphene supports in vitro proliferation and osteogenic differentiation of goat adult mesenchymal stem cells: potential for bone tissue engineering.J Appl Toxicol.2015;35(4):367-374.[25] Lee WC,Lim CH,Shi H,et al.Origin of Enhanced Stem Cell Growth and Differentiation on Graphene and GrapheneOxide. Acs Nano. 2011;5(9):7334-7341.[26] Nayak TR,Andersen H,Makam VS,et al.Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem cells.ACS Nano. 2011;5(6):4670-4678．[27] 吕成奇,陆家瑜,于佳,等.自撑式石墨烯水凝胶诱导人脂肪干细胞成骨分化的体外研究[J].口腔医学, 2014,34(7):486-491.[28] Liu Y,Chen T,Du F,et al.Single-Layer Graphene Enhances the Osteogenic Differentiation of Human Mesenchymal Stem Cells In Vitro and In Vivo.J Biomed Nanotechnol. 2016;12(6):1270-1284.[29] Kenry,Lee WC,Loh KP,et al.When stem cells meet graphene: Opportunities and challenges in regenerative medicine. Biomaterials. 2018;155:236-250.[30] Xie H,Cao T,Rodríguez-Lozano FJ,et al.Graphene for the development of the next-generation of biocomposites for dental and medical applications. Dent Mater. 2017;33(7):765-774.[31] Kumar S,Azam MD,Raj S,et al.3D scaffold alters cellular response to graphene in a polymer composite for orthopedic applications.J Biomed Mater Res B Appl Biomater. 2015;104(4): 732-749.[32] Feng P,Peng S,Wu P,et al.A nano-sandwich construct built with graphenenanosheets and carbon nanotubes enhances mechanical properties of hydroxyapatite–polyetheretherketone scaffolds.Int J Nanomedicine.2016;28(6):3487-500.[33] Kumar S,Raj S,Kolanthai E,et al.Chemical functionalization of graphene to augment stem cell osteogenesis and inhibit biofilm formation on polymer composites for orthopedic applications.Acs Appl Mater Interfaces.2015;7(5):3237-3252.[34] Kumar S,Raj S,Sarkar K,et al.Engineering a multi-biofunctional composite using poly(ethylenimine) decorated graphene oxide for bone tissue regeneration. Nanoscale.2016;8(12):6820-6836.[35] Duan S,Yang X,Mei F,et al. Enhanced osteogenic differentiation of mesenchymal stem cells on poly(L-lactide) nanofibrous scaffolds containing carbon nanomaterials.J Biomed Mater Res A. 2015; 103(4):1424-1435.[36] Shao W,He J,Sang F,et al.Enhanced bone formation in electrospun poly(l-lactic-co-glycolic acid)-tussah silk fibroin ultrafine nanofiber scaffolds incorporated with graphene oxide. Mater SciEng C.2016;62(6):823-834.[37] Lyu CQ,Lu JY,Cao CH,et al.Induction of osteogenic differentiation of human adipose-derived stem cells by a novel self-supporting graphene hydrogel film and the possible underlying mechanism.ACS Appl Mater Interfaces. 2015;7(36):20245-20254.[38] Nair M,Nancy D,Krishnan AG,et al.Graphene oxide nanoflakes incorporated gelatin–hydroxyapatite scaffolds enhance osteogenic differentiation of human mesenchymal stem cells. Nanotechnology. 2015;26(16):1-10.[39] Xie C,Lu X,Han L,et al.Biomimetic Mineralized Hierarchical Graphene Oxide/Chitosan Scaffolds with Adsorbability for Immobilization of Nanoparticles for Biomedical Applications. ACS Appl Mater Interfaces. 2016;8(3):1707-1717.[40] Xie Y,Li H,Zhang C,et al.Graphene-reinforced calcium silicate coatings for load-bearing implants. Biomed Mater. 2014;9(2):1-7.[41] Shie MY,Chiang WH,Chen IWP,et al.Synergistic acceleration in the osteogenic and angiogenic differentiation of human mesenchymal stem cells by calcium silicate–graphene composites.Mater Sci Eng C.2017;73(4):726-735.[42] Saravanan S,Anjali C,Vairamani M,et al.Scaffolds containing chitosan, gelatin and graphene oxide for bone tissue regeneration in vitro and in vivo.Int J BiolMacromol. 2017;104(Pt B):1975-1985.[43] Zancanela DC,Simão AMS,Francisco CG,et al.Graphene oxide and titanium: synergistic effects on the biomineralization ability of osteoblast cultures.J Mater Sci Mater Med. 2016;27(4):1-9. [44] Ren N,Li J,QiuJ,et al.Growth and accelerated differentiation of mesenchymal stem cells on graphene-oxide-coated titanate with dexamethasone on surface of titanium implants. Dent Mater 2017; 33(7):525-535.[45] Zhang W,Chang Q,Xu L,et al.Graphene Oxide-Copper Nanocomposite-Coated Porous CaP Scaffold for Vascularized Bone Regeneration via Activation of Hif-1α.Adv Healthc Mater. 2016;5(11):1299-1309.[46] Kumar S,Chatterjee K.Strontium eluting graphene hybrid nanoparticles augment osteogenesis in a 3D tissue scaffold. Nanoscale.2014;7(5):2023-2033.[47] Chen J,Zhang X,Cai H,et al.Osteogenic activity and antibacterial effect of zinc oxide/carboxylatedgraphene oxide nanocomposites:Preparation and in vitro evaluation.Colloids Surfaces B Biointerfaces.2016;147(6):397-407.[48] Zhang S,Yang Q,Zhao W,et al.In vitro and in vivo biocompatibility and osteogenesis of graphene-reinforced nanohydroxyapatite polyamide66 ternary biocomposite as orthopedic implant material. Int J Nanomedicine. 2016;11(7):3179-3189.[49] Nayak TR,Andersen H,Makam VS,et al.Graphene for controlled and accelerated osteogenic differentiation of humanmesenchymal stem cells.ACS Nano. 2011;5(6):4670-4678.[50] Wang CH,Guo ZS,Pang F,et al.Effects of Graphene Modification on the Bioactivation of Polyethylene-Terephthalate-Based Artificial Ligaments.ACS Appl Mater Interfaces. 2015;7(28):15263-15276.[51] Liu H,Cheng J,Chen F,et al.Gelatin functionalizedgraphene oxide for mineralizationof hydroxyapatite:biomimetic and in vitroevaluation. Nanoscale.2014;6(10):5315-5322.[52] Nie W,Peng C,Zhou X,et al.Three-dimensional porous scaffold by self-assembly of reduced graphene oxide andnano-hydroxyapatite composites for bone tissue engineering. Carbon N Y.2017;116(5): 325-337.[53] Lee JH,Shin YC,Jin OS,et al.Reduced graphene oxide-coated hydroxyapatite composites stimulate spontaneous osteogenic differentiation of human mesenchymal stem cells. Nanoscale. 2015;7(6):11642-11651.[54] Lee JH,Shin YC,Lee SM,et al.Enhanced Osteogenesis by Reduced Graphene Oxide/Hydroxyapatite Nanocomposites. Sci Rep.2016;5(5):1-12.[55] Oyefusi A,Olanipekun O,Neelgund GM,et al.Hydroxyapatite grafted carbon nanotubes and graphenenanosheets: Promising bone implant materials. Spectrochim Acta A Mol Biomol Spectrosc. 2014;132(6):410-416.[56] Tatavarty R,Ding H,Lu G,et al.Synergistic acceleration in the osteogenesis of human mesenchymal stem cells bygraphene oxide-calcium phosphate nanocomposites.Chem Commun. 2014; 50(4):8484-8487.[57] Li M,Wang Y,Liu Q,et al.In situ synthesis and biocompatibility of nano hydroxyapatite on pristine and chitosan functionalizedgraphene oxide.J Mater Chem B. 2013;1:475-484.[58] Dong W,Hou L,Li T,et al.A Dual Role of Graphene Oxide Sheet Deposition on Titanate Nanowire Scaffolds for Osteo-implantation: Mechanical Hardener and Surface Activity Regulator.Sci Rep. 2015;5(6):1-13.[59] Zhou Q,Yang P,Li X,et al.Bioactivity of periodontal ligament stem cells on sodium titanate coated with graphene oxide.Sci Rep. 2016;6(7):193-203.[60] La WG,Park S,Yoon HH,et al.Delivery of a therapeutic protein for bone regeneration from a substrate coated with graphene oxide.Small.2013;9(5):4051-4060.[61] La WG,Kim BS,Jin M,et al.Delivery of bone morphogenetic protein-2 and substance P using graphene oxide for bone regeneration.Int J Nanomedicine.2014;6(5):107-116.[62] Qiu J,Geng H,Wang D,et al.Layer-Number Dependent Antibacterial and Osteogenic Behaviors of Graphene Oxide Electrophoretic Deposited on Titanium.ACS Appl Mater Interfaces. 2017;9(6):12253-12263.[63] Subbiah R,Du P,Van SY,et al.Fibronectin-tethered graphene oxide as an artificial matrix for osteogenesis.Biomed Mater. 2014;9(3): 650-663.[64] Kim SY,Yoo JY,Ohe JY,et al.Differential expression of osteo-modulatory molecules in periodontal ligament stem cells in response to modified titanium surfaces.Biomed Res Int. 2014;9(1): 1-12.[65] Li K,Yan J,Wang C,et al.Graphene modified titanium alloy promote the adhesion, proliferation and osteogenic differentiation of bone marrow stromal cells.BiochemBiophys Res Commun. 2017;489(6):187-192. |
.jpg)
.jpg)
.jpg)