中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (51): 9549-9552.doi: 10.3969/j.issn.1673-8225.2011.51.012

• 复合支架材料 composite scaffold materials • 上一篇    下一篇

记忆合金材料弹力金属支架在犬肺组织瓣重建气管缺损中的应用

纪子钊1，陈  刚2，张苏宁1，石文君1   

  1. 1中国医科大学盛京医院胸外科，辽宁省沈阳市 110004
    2九江市第一人民医院心胸外科，江西省九江市 332000
  • 收稿日期:2011-08-25 修回日期:2011-11-06 出版日期:2011-12-17 发布日期:2011-12-17
  • 通讯作者: 石文君，博士生导师，教授，中国医科大学盛京医院胸外科，辽宁省沈阳市 110004 shiwj@ cmu2h.com
  • 作者简介:纪子钊☆，男，1973年生，辽宁省辽阳市人，汉族，2007年中国医科大学毕业，博士，主治医师，主要从事胸外科食管重建研究。 versace_et@ 163.com
  • 基金资助:

    卫生部立项资助项目(WKZ-2000-1-17)。

Application of a memory alloy elastic metal stent in reconstruction of tracheal defects by pulmonary tissue flaps in dogs

Ji Zi-zhao1, Chen Gang2, Zhang Su-ning1, Shi Wen-jun1   

  1. 1Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang  110004, Liaoning Province, China
    2Department of Cardiothoracic Surgery, First People’s Hospital of Jiujiang, Jiujiang  332000, Jiangxi Province, China
  • Received:2011-08-25 Revised:2011-11-06 Online:2011-12-17 Published:2011-12-17
  • Contact: Shi Wen-jun, Doctoral supervisor, Professor, Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China shiwj@cmu2h.com
  • About author:Ji Zi-zhao☆, Doctor, Attending physician, Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China versace_et@ 163.com
  • Supported by:

    Financed Program of Ministry of Health, No. WKZ-2000-1-17*

PDF

426

被引次数

10

摘要：

背景：生物相容性好的内衬支架是肺组织瓣成功修补气管缺损的关键，记忆合金支架成为目前研究热点。
目的：探讨应用自体肺组织瓣内衬金属弹力支架替代气管缺损的可行性。
方法：由中国医科大学附属盛京医院动物实验室提供杂种成年犬14只，雄性8只，雌性6只，体质量12~26 kg，气管整段切除3 cm或5 cm，采用自体肺组织瓣内衬金属弹力支架替代气管缺损方法行胸段气管重建。
结果与结论：4只犬死亡，死于并发症及其他原因，10只成活，吻合口愈合良好，食管钡透通畅。结果表明自体肺组织瓣内衬金属弹力支架替代气管缺损是一种可行的气管重建方法。

关键词: 气管缺损, 肺, 组织瓣, 气管重建, 记忆合金支架

Abstract:

BACKGROUND: Lined stent containing good biocompatibility is the key of successful repair of tracheal defect by pulmonary tissue flap. Memory alloy stent is the research hotspot now.
OBJECTIVE: To explore the possibility of autologous pulmonary tissue flap lined with elastic metal stent in replacing tracheal defect.
METHODS: Fourteen hybrid adult dogs came from animal laboratory of Shengjing Hospital of China Medical University were involved. Eight dogs were male and six ones were female with weight of 12-26 kg. The entire trachea of 3 cm or 5 cm was removed in all dogs. Thoracic tracheal reconstruction was performed with autologous pulmonary tissue flap lined with elastic metal stent to replace the tracheal defect.
RESULTS AND CONCLUSION: Four dogs died of the complications and other reasons. Ten dogs survived, and their stomas were good and the barium flux was unobstructed. The replacement of tracheal defect by autologous pulmonary tissue flap lined with elastic metal stent is a possible tracheal reconstruction method.

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