中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (42): 7813-7816.doi: 10.3969/j.issn.1673-8225.2011.42.006

• 膜生物材料 membrane biomaterials • 上一篇    下一篇

氟硅酮丙烯酸脂材料制作角膜塑形镜控制近视效果及其安全性

刘维锋，钟  翔，石  浔，胡爱梅   

  1. 南昌大学第三附属医院眼科，江西省南昌市  330008
  • 收稿日期:2011-04-10 修回日期:2011-07-13 出版日期:2011-10-15 发布日期:2011-10-15
  • 通讯作者: 钟翔，副主任医师，南昌大学第三附属医院眼科，江西省南昌市 330008 zhongxiang@ yahoo.cn
  • 作者简介:刘维锋★，男，1977年生，江西省兴国市人，汉族，2007年重庆医科大学毕业，硕士，主治医师，主要从事近视防治方面的研究。 liuwfso@ yahoo.cn

Effect and safety of orthokeratology made of fluorosilicone acrylate on myopia control 

Liu Wei-feng, Zhong Xiang, Shi Xun, Hu Ai-mei   

  1. Department of Ophthalmology, the Third Hospital Affiliated to Nanchang University, Nanchang  330008, Jiangxi Province, China
  • Received:2011-04-10 Revised:2011-07-13 Online:2011-10-15 Published:2011-10-15
  • Contact: Zhong Xiang, Associate chief physician, Department of Ophthalmology, the Third Hospital Affiliated to Nanchang University, Nanchang 330008, Jiangxi Province, China zhongxiang@ yahoo.cn
  • About author:Liu Wei-feng★, Master, Attending physician, Department of Ophthalmology, the Third Hospital Affiliated to Nanchang University, Nanchang 330008, Jiangxi Province, China liuwfso@yahoo.cn

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569

被引次数

11

摘要：

背景：氟硅酮丙烯酸脂透气性材料成为制作角膜塑形镜的理想材料，其对眼屈光和眼生理的影响受到关注。
目的：研究角膜塑形术控制近视发展的临床效果及安全性。
方法：观察18例35眼佩戴1年角膜塑形镜的青少年中、低度近视裸眼视力、屈光度变化、眼轴长度、角膜内皮计数、眼压、角膜Q值等变化。
结果与结论：1年后裸眼视力与佩戴前矫正视力比较差异无显著性意义(t=-0.27、P=0.78)；佩戴前后1年屈光度、眼轴长度、角膜内皮计数、眼压比较差异无显著性意义(t=1.37、P=0.18；t=-0.94、P=0.35；t=-0.52、P=0.6；t=1.00、P=0.32)；佩戴前后1年角膜Q值比较差异有显著性意义(t=-8.03、P=0.00)。提示氟硅酮丙烯酸脂透气性材料角膜塑形镜控制近视安全、有效，对眼生理影响小。

关键词: 氟硅酮丙烯酸脂, 角膜塑形, 安全, 有效, 矫正视力

Abstract:

BACKGROUND: Fluorosilicone acrylate is a perfect plastic material for orthokeratology, and its influence on diopter and physiology of the eye is attracted.
OBJECTIVE: To study the clinical safety and effects of orthokeratology to control myopia development.  
METHODS: The clinical data of 18 patients (35 eyes) wearing orthokeratology contact lens (Ortho-k CL) for 1 year were analyzed  in low-and middle-degree myopia of the teenage, including uncorrected visual acuity (UCVA), diopter, axial length, the number of corneal endothelial cells, intraocular pressure, cornea Q value.
RESULTS AND CONCLUSION: There was no significant difference in the UCVA after wearing Ortho-k CL for 1 year to corrected visual acuity before wearing (t=-0.27, P=0.78). Compared to before wearing Ortho-k CL, there was no significant difference in diopter, axial length, the number of corneal endothelial cells, intraocular pressure at 1 year after wearing (t=1.37, P=0.18; t=-0.94, P=0.35; t=-0.52, P=0.6; t=1.00, P=0.32). There was significant difference in cornea Q value (t=-8.03, P=0.00) between before and after wearing Ortho-k CL. Results showed that fluorosilicone acrylate Ortho-k CL is effective and safe to control myopia development with little influence on eye physiology.

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