中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (11): 2064-2068.doi: 10.3969/j.issn.1673-8225.2011.11.041

• 组织构建循证医学 evidence-based medicine in tissue construction • 上一篇    下一篇

夹脊穴结合局部围针治疗带状疱疹后遗神经痛的Meta分析

朱  毅1，2，朱黎婷1，李  凝1，李  怡1，金宏柱1   

  1. 1南京中医药大学第二临床医学院，江苏省南京市  210029
    2江苏省中医院针灸康复科，江苏省南京市  210029
  • 收稿日期:2010-10-05 修回日期:2010-11-10 出版日期:2011-03-12 发布日期:2011-03-12
  • 通讯作者: 金宏柱，教授，博士生导师，南京中医药大学第二临床医学院，江苏省南京市 210029 jinhongzhubox@yahoo.com.cn
  • 作者简介:朱毅★，男，1981年生，江苏省南京市人，汉族，2007年香港理工大学毕业，硕士，讲师，主管治疗师，主要从事康复治疗技术方面的研究。 zhuyi1010@163.com

Jiaji points combined with surrounding needling for the treatment of postherpetic neuralgia: A Meta-analysis 

Zhu Yi1, 2, Zhu Li-ting1, Li Ning1, Li Yi1, Jin Hong-zhu1   

  1. 1Second Clinical Medical College of Nanjing University of Traditional Chinese Medicine, Nanjing  210029, Jiangsu Province, China
    2Department of Acupuncture and Rehabilitation, Jiangsu Provincial Hospital of Traditional Chinese Medicine, Nanjing  210029, Jiangsu Province, China
  • Received:2010-10-05 Revised:2010-11-10 Online:2011-03-12 Published:2011-03-12
  • Contact: Jin Hong-zhu, Professor, Doctoral supervisor, Second Clinical Medical College of Nanjing University of Traditional Chinese Medicine, Nanjing 210029, Jiangsu Province, China jinhongzhubox@yahoo.com.cn
  • About author:Zhu Yi★, Master, Lecturer, Chief therapeutist, Second Clinical Medical College of Nanjing University of Traditional Chinese Medicine, Nanjing 210029, Jiangsu Province, China zhuyi1010@163.com

PDF

966

被引次数

20

摘要：

背景：临床应用夹脊穴结合局部围针治疗带状疱疹后遗神经痛取得了良好的疗效，但其效果是否优于西药尚不明确。
目的：系统评价夹脊穴结合局部围针治疗带状疱疹后遗神经痛的有效性。
方法：计算机检索中国知网数据库、维普全文期刊数据库、中国生物医学文献数据库、Pubmed医学文献检索服务系统、美国斯坦福大学的Highwire数据库，手工检索南京中医药大学图书馆过刊资料库及相关会议论文集，检索时间为建库至2010-07，收集夹脊穴结合局部围针治疗带状疱疹后遗神经痛的临床随机对照试验，并按照循证医学原则对文献质量进行评价。统计学分析采用RevMan 4.2软件。采用总有效率、临床治愈率、疼痛目测类比评分、临床症状评分等作为结局评价指标。
结果与结论：共纳入13个随机对照试验(共858例)。Meta分析结果显示，夹脊穴结合局部围针治疗带状疱疹后遗神经痛在总有效率[RR=1.26，95%CI(1.19，1.34)]、临床治愈率[RR=1.93，95%CI(1.64，2.27)]、疼痛目测类比评分[WMD=3.13，95%CI(2.38，3.87)]方面明显优于对照组。总有效率分类比较显示，夹脊穴结合围针的效果与物理治疗差异无显著性意义[RR=1.60，95%CI(0.43，6.02)]，但明显优于卡马西平[RR=1.45，95%CI(1.22，1.72)]。说明夹脊穴结合局部围针治疗带状疱疹后遗神经痛的疗效优于西药，但尚需要更多高质量的随机双盲对照试验来进一步证实其疗效。

关键词: 夹脊穴, 围针, 带状疱疹后遗神经痛, 随机对照试验, Meta分析

Abstract:

BACKGROUND: Jiaji points plus surrounding needling has received good therapeutic effect in the treatment of postherpetic neuralgia. However, whether its effect is superior to the western medicine remains poorly understood.
OBJECTIVE: To evaluate the curative efficacy of Jiaji points plus surrounding needling on treating postherpetic neuralgia.
METHODS: Randomized controlled trials (RCTs) involving Jiaji points and surrounding needling on postherpetic neuralgia were identified from CNKI, VIP, and CBM. We also hand searched relevant journals and conference proceedings. The Cochrane Collaboration’s RevMan 4.2.2 software was used for data analyses. Total effective rate, clinical cure rate, visual analog scale, and clinical symptom score served as outcome assessment indexes.
RESULTS AND CONCLUSION: A total of 13 trials involving 858 patients were included. Meta-analyses showed that, Jiaji points plus surrounding needling on treating postherpetic neuralgia showed superiority to the control group in total effective rate [RR=1.26, 95%CI (1.19, 1.34)], clinical cure rate [RR=1.93, 95%CI (1.64，2.27)], and visual analog scale [WMD=3.13, 95%CI (2.38, 3.87)]. There was no significant difference between the Jiaji points plus surrounding needling and physical therapy [RR=1.60, 95%CI (0.43, 6.02)], but superior to carbamazepine [RR=1.45, 95%CI (1.22, 1.72)]. The profit treated by Jiaji points plus surrounding needling on postherpetic neuralgia is superior to western medicine. However, further large-scale trials are required to define therapeutic effects.

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