中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (17): 3139-3142.doi: 10.3969/j.issn.1673-8225.2010.17.025

• 脊柱损伤基础实验 basic experiments of spinal injury • 上一篇    下一篇

锦州地区青少年椎间盘突出危险因素的Logistic回归分析

王岩松，梅晰凡   

  1. 辽宁医学院附属第一医院骨科，辽宁省锦州市 121000
  • 出版日期:2010-04-23 发布日期:2010-04-23
  • 作者简介:王岩松☆，男，1980年生，辽宁省兴城市人，满族，中国医科大学在读博士，医师，主要从事脊柱外科的研究。 wys990709@126.com

Logistic regression analysis of risk factors for lumbar disc herniation in adolescents in Jinzhou city

Wang Yan-song, Mei Xi-fan   

  1. Department of Orthopaedics, First Affiliated Hospital of Liaoning Medical University, Jinzhou 121000, Liaoning Province, China
  • Online:2010-04-23 Published:2010-04-23
  • About author:Wang Yan-song☆, Studying for doctorate, Physician, Department of Orthopaedics, First Affiliated Hospital of Liaoning Medical University, Jinzhou 121000, Liaoning Province, China wys990709@126.com

PDF

435

被引次数

6

摘要：

背景：成人与青少年椎间盘突出的发病机制和危险因素差别很大，国内应用logistic回归分析青少年椎间盘突出危险因素的研究较少。
目的：多因素非条件Logistic回归分析锦州地区青少年椎间盘突出发病的危险因素。
方法：选择青少年椎间盘突出患者94例作为实验组，男56例，女38例；年龄9~18岁。居住地为锦州市。对照组患者选自同期因其他非椎间盘突出疾病入院的同年龄组同居住地患者共100例。采用多因素非条件Logistic回归分析对椎间盘突出发病的可能相关因素进行分析，以OR > 1为椎间盘突出发生的危险因素：OR < 1为椎间盘突出发生的保护因素。
结果与结论：194例患者均进入结果分析。多因素非条件Logistic回归分析显示：与对照组相比，椎间盘突出患者家族遗传OR =6.427，P=0.015；创伤因素OR=17.196，P=0.011；先天畸型 OR=31.429，P=0.002；运动过量OR=12.644，P=0.027。结果表明，家族遗传、创伤、先天畸型和运动过量是锦州地区青少年椎间盘突出发病的危险因素。以此为依据制定相应的预防方案十分必要。

关键词: 椎间盘突出, 危险因素, 回归分析, 青少年, 锦州

Abstract:

BACKGROUND: The pathogenesis and risk factors for lumbar disc herniation are significantly different between adults and teenagers. Previous studies seldomly refer to risk factors for lumbar disc herniation in adolescents by using logistic regression analysis.
OBJECTIVE: To investigate the risk factors for lumbar disc herniation in adolescents in Jinzhou by using logistic regression analysis.
METHODS: A total of 94 patients with lumbar disc herniation, including 56 males and 38 females, aging 9-18 years, were considered as the experimental group. A total of 100 patients suffering from other diseases were considered as the control group. Logistic regression analysis was employed to analyze risk factors for lumbar disc herniation onset, suggesting that OR >1 was taken as the risk factor for lumbar disc herniation, whereas OR <1 as the protective factor for lumbar disc herniation.
RESULTS AND CONCLUSION: All the 194 patients were involved in the final analysis. The result of logistic regression analysis showed that compared with control groups, the patients with lumbar disc herniation were statistically associated with familial predisposition (OR = 6.427, P = 0.015), trauma (OR = 17.196, P = 0.011), congenital malformations (OR = 31.429, P = 0.002), and over-exercise (OR = 12.644, P = 0.027). Trauma, congenital malformations, familial predisposition, and over-exercise were the risk factors for lumbar disc herniation in children and adolescents in Jinzhou. So it is necessary to implement a comprehensive prevention program, such as lifestyle and dietary habit modification, and proper activity.

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