中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (17): 3131-3134.doi: 10.3969/j.issn.1673-8225.2010.17.023

• 骨与关节生物力学 bone and joint biomechanics • 上一篇    下一篇

正常股骨头与坏死股骨头松质骨的蠕变特性：45°方向取样比较

于  涛1，孙长江1，马洪顺2   

  1. 1吉林大学中日联谊医院，吉林省长春市 130031；2吉林大学南岭校区工程力学系，吉林省长春市 130022
  • 出版日期:2010-04-23 发布日期:2010-04-23
  • 通讯作者: 马洪顺，教授，吉林大学南岭校区工程力学系，吉林省长春市 130022 mahs@jlu.edu.cn
  • 作者简介:于 涛☆，男，1975年生，吉林省长春市人，汉族，2003年吉林大学中日联谊医院毕业，博士，副教授，主要从事骨科临床与生物力学。

Creep characteristics of cancellous bone at 45° between normal and necrotic femoral head  

Yu Tao1, Sun Chang-jiang1, Ma Hong-shun2   

  1. 1 China-Japan Union Hospital of Jilin University, Changchun   130031, Jilin Province, China; 2 Department of Engineering Mechanics, Nanling Campus of Jilin University, Changchun   130022, Jilin Province, China
  • Online:2010-04-23 Published:2010-04-23
  • Contact: Ma Hong-shun, Professor, Department of Engineering Mechanics, Nanling Campus of Jilin University, Changchun 130022, Jilin Province, China mahs@jlu.edu.cn
  • About author:Yu Tao☆, Doctor, Associate professor, China-Japan Union Hospital of Jilin University, Changchun 130031, Jilin Province, China

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摘要：

背景：临床人工关节置换和人工关节的研究都需要了解坏死股骨头松质骨以不同方向取样的蠕变力学特性，因此有必要以45°方向取样对松质骨的力学性质进行研究。
目的：以三参数模型建立了蠕变方程，比较正常股骨头和坏死后股骨头45°方向蠕变性质。
方法：正常股骨头和坏死股骨头各8个，沿股骨头松质骨45°方向取样，在电子万能试验机上进行蠕变实验。模拟人体体温在36.5 ℃的温度场下，以0.1 MPa/s的应力增加速度对标本施加常应力，设定时间为7 200 s，采集100个实验数据。采用三参数模型计算蠕变方程。
结果与结论：正常股骨头和坏死股骨头蠕变曲线均以指数关系变化的，在最初600 s应变变化较快，随时间延长应变缓慢上升，最后进入平衡阶段。坏死股骨头松质骨7 200 s蠕变量小于正常股骨头松质骨。提示三参数模型计算简便，能很好地拟合股骨头的45°方向蠕变变化，通过建立这种理想化的方程，可以定量说明坏死股骨头的黏弹性较差。

关键词: 正常股骨头, 坏死股骨头, 股骨头松质骨, 45°, 方向, 蠕变特性, 骨组织构建

Abstract:

BACKGROUND: The creep characteristics of cancellous bone from necrotic femoral head are important for clinical artificial joint replacement. Therefore, it is necessary to study mechanical properties of cancellous bone at 45 ° direction.
OBJECTIVE: To compare creep properties of normal femoral head and necrotic femoral head at 45 ° direction based on three-parameter model established creep equation.
METHODS: A total of 8 normal and 8 necrotic femoral heads were used. The cancellous bone was harvested at 45 ° and subjected to creep test on electronic universal testing machine. With simulated temperature field of human body temperature at 36.5 ℃, stress was imposed on the samples by an increase of 5%/s for 7 200 seconds. 100 experimental data were collected, and stress relaxation equation was calculated using three-parameter model.
RESULTS AND CONCLUSION: The creep curve of the femoral head of normal and necrotic changes was exponential relation. Changes were fast in the first 600 seconds, and strain increased slowly with time, finally entered into balance stage. 7 200 s creep of cancellous bone from necrotic femoral head was less than normal femoral head cancellous bone. Three-parameter model calculation is simple and can well fit the creep of changes in the femoral head. The establishment of such idealized equation quantitatively shows poor visco-elasticity of the necrotic femoral head.

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