中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (3): 521-524.doi: 10.3969/j.issn.1673-8225.2010.03.034

• 生物材料综述 biomaterial review • 上一篇    下一篇

医用敷料研究的现状与进展

柯林楠，冯晓明，王春仁   

  1. 中国药品生物制品检定所医疗器械检测中心，北京市  100050
  • 出版日期:2010-01-15 发布日期:2010-01-15
  • 作者简介:柯林楠★，女，1977年生，北京市人，汉族，2004年中国科学院生态环境研究中心毕业，硕士，助理研究员，主要从事医疗器械的化学性能检测。 kelinnan@sina.com

Recent research and progress of medical dressings

Ke Lin-nan, Feng Xiao-ming, Wang Chun-ren   

  1. Center for Medical Devices Testing, National Institute for the Control of Pharmaceutical and Biological Products, Beijing  100050, China
  • Online:2010-01-15 Published:2010-01-15
  • About author:Ke Lin-nan★, Master, Assistant researcher, Center for Medical Devices Testing, National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China kelinnan@sina.com

PDF

1305

被引次数

114

摘要：

背景：医用敷料作为伤口处的覆盖物，在伤口愈合过程中，可以替代受损的皮肤起到暂时性屏障作用，避免或控制伤口感染，提供有利于创面愈合的环境。随着人口的老龄化和慢性溃疡性伤口的增多，医用敷料的市场价值也变得越来越重要。
目的：论述医用敷料现状及近年来的研究进展，探索其进一步的发展方向。
方法：应用计算机检索Elsevier数据库和中国期刊全文数据库中1980-01/2009-01关于医用敷料方面的文章，在标题和摘要中以“医用敷料，胶原蛋白，壳聚糖，水凝胶”或“medical dressing，chitosan”为检索词进行检索。选择文章内容与医用敷料种类、特点、临床应用相关，同一领域文献则选择近期发表或发表在权威杂志文章。根据纳入标准选择35篇文献用于进行综述。
结论和结论：就目前临床使用及研究的医用敷料，根据其所用的材料将其分成了天然高分子，合成高分子，无机材料和复合材料，分别对它们的性能和临床应用做了比较详细的介绍，并对敷料类产品质量控制中出现的问题进行了讨论，展望了敷料类产品的未来发展方向。文章可为医用敷料类产品的研发提供理论依据，同时为制造商在质量控制、标准建立以及政府监管部门对该类产品的监督监管提供理论基础。

关键词: 医用敷料, 伤口愈合, 天然高分子, 合成高分子, 无机材料, 复合材料

Abstract:

BACKGROUND: Medical dressings can play a temporality barrier function as skin substitute in wound healing, which can avoid or control wound infection. With the increasing of aging and chronic ulcer wound, medical dressings play a more important role.
OBJECTIVE: To review the recent research and progress of medical dressings, in addition, to explore its developing direction.
METHODS: Elsevier database and CNKI was retrieved by computer with key words of “medical dressing, collagen, gel and chitosan” to search papers published between January 1980 and January 2009. Related papers addressing medical dressings were selected. According to inclusion criteria, 35 literatures were selected in this study.
RESULTS AND CONCLUSION: Currently, the medical dressings can be classified into natural polymer, synthetic macromolecule, inorganic material and composite. Their performances and clinical application were reviewed respectively. The quality control and future development of medical dressing products were also discussed. This paper can provide a theoretical foundation for the researcher in study and development of medical dressings, manufacturer in the quality control and government in product quality supervision.

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