中国组织工程研究 ›› 2025, Vol. 29 ›› Issue (33): 7181-7188.doi: 10.12307/2025.860

• 骨科植入物 orthopedic implant • 上一篇    下一篇

经Kambin三角穿刺椎体成形治疗骨质疏松压缩性骨折:安全性和有效性评价

江泽华,杜文君,任志帅,崔皓竣,朱如森   

  1. 天津市人民医院脊柱外科,天津市   300121
  • 收稿日期:2024-08-09 接受日期:2024-11-22 出版日期:2025-11-28 发布日期:2025-04-12
  • 通讯作者: 朱如森,主任医师,硕士生导师,天津市人民医院脊柱外科,天津市 300121
  • 作者简介:江泽华,男,1983年生,湖北省天门市人,汉族,南开大学毕业,硕士,主治医师,主要从事脊柱脊髓疾病的基础与临床、退行性脊柱疾病的研究。
  • 基金资助:
    天津市人民医院院级科研基金(2019JZPY08),项目负责人:江泽华;天津市卫生健康委员会科技项目青年项目(TJWJ2022QN040),项目负责人:任志帅

Percutaneous vertebroplasty via Kambin's triangle for treatment of osteoporotic compression fractures: evaluation of safety and effectiveness

Jiang Zehua, Du Wenjun, Ren Zhishuai, Cui Haojun, Zhu Rusen   

  1. Department of Spine Surgery, Tianjin Union Medical Center, Tianjin 300121, China
  • Received:2024-08-09 Accepted:2024-11-22 Online:2025-11-28 Published:2025-04-12
  • Contact: Zhu Rusen, Chief physician, Master’s supervisor, Department of Spine Surgery, Tianjin Union Medical Center, Tianjin 300121, China
  • About author:Jiang Zehua, MS, Attending physician, Department of Spine Surgery, Tianjin Union Medical Center, Tianjin 300121, China
  • Supported by:
    Tianjin Union Medical Center Research Fund, No. 2019JZPY08 (to JZH); Tianjin Municipal Health Commission Science and Technology Project (Youth Project), No. TJWJ2022QN040 (to RZS)

摘要:


文题释义:

Kambin三角:又称为安全三角,最早由Parviz Kambin于1973年提出。Kambin三角由3部分围成的直角三角形构成:①斜边:出口神经根;②高:硬膜囊和走行根;③底边:下位椎体的上终板。
经皮椎体成形:穿刺皮肤后,经过椎体椎弓根或者椎弓根旁入路把骨水泥注入椎体的一种手术。经皮椎体成形术分为2类:①单纯通过椎弓根或者椎弓根旁入路,将骨水泥注入椎体;②经皮椎体后凸成形术:通俗也称为经皮椎体成形术,后凸成形术与单纯椎体成形术相比,会有球囊或者扩张器膨胀过程,通过球囊或者扩张器将压缩椎体部分或者完全复位,再打入骨水泥。与单纯椎体成形术相比,其复位效果更佳,骨水泥渗漏的概率更低。


背景:目前腰椎压缩骨折手术治疗的主要目的是改善症状、减少疼痛、提高生活质量,在最大限度内降低手术风险,减少手术暴露时间。

目的:探讨经Kambin三角穿刺椎体成形治疗老年性脊柱畸形合并骨质疏松椎体压缩性骨折患者的安全性及有效性。
方法:回顾性分析天津市人民医院2019年1月至2022年12月收治的脊柱畸形合并骨质疏松椎体压缩性骨折患者31例,其中男21例,女10例;年龄60-84 (70.0±10.3)岁;病程1-6 (3.5±1.7)周;共有35个病变的节段椎体。压缩骨折椎体范围:L1骨折10例、L2骨折12例、L1+L2骨折2例、L3骨折5例、L1+L3骨折2例。根据入路方式分为2组:A组(经Kambin三角入路行椎体成形)15例,B组(经传统椎弓根穿刺行椎体成形)16例,两组患者均行单侧入路椎体成形术。记录两组患者的手术时间、射线暴露次数,明确有无骨水泥渗漏,是否出现神经及血管损伤等并发症,术后CT观察骨水泥弥散及硬化的情况。

结果与结论:①A组手术时间21-30 min/椎,平均(25.0±5.7) min;B组手术时间25-43 min/椎,平均(33.0±7.2) min;单个椎体穿刺时间B组要长于A组,差异有显著性意义(P < 0.05);②A组每个椎体术中平均射线暴露次数(6.2±1.6)次,B组每个椎体术中平均射线暴露次数为(9.3±1.8)次,两组比较差异有显著性意义(P < 0.05);③A组未发现骨水泥渗漏,B组出现2例骨水泥渗漏,其中1例椎管内少量渗漏,未出现明显神经症状,渗漏率为13%;两组均出现1例皮下血肿;④术后CT观察骨水泥在椎体中的分布情况,A、B组骨水泥能在椎体中均匀扩散的分布率分别为71%和33%,两组比较差异有显著性意义(P < 0.05);⑤提示经Kambin三角入路穿刺行经皮椎体成形治疗的手术时间短,骨水泥在椎体内弥散分布填充好,并发症的风险发生率低,辐射暴露量少,单侧穿刺就能达到满意的效果。

https://orcid.org/0000-0002-5336-740X (江泽华) 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

关键词: 骨质疏松压缩骨折, Kambin 三角, 椎体成形术, 临床疗效, 并发症, 骨科植入物, 脊柱植入物

Abstract: BACKGROUND: Currently, the main purpose of surgical treatment for lumbar compression fractures is to improve symptoms, reduce pain, improve quality of life, minimize surgical risks, and reduce surgical exposure time.
OBJECTIVE: To explore the safety and clinical efficacy of percutaneous vertebroplasty via Kambin’s triangle in the treatment of senile spinal deformity accompanied by osteoporotic vertebral compression fractures. 
METHODS: A retrospective analysis was conducted on 31 patients with spinal deformity and osteoporotic vertebral compression fractures who were admitted to Tianjin Union Medical Center from January 2019 to December 2022. There were 21 males and 10 females, aged between 60 and 84 (70.0±10.3) years old. The duration of illness ranged from 1 to 6 (3.5±1.7) weeks. A total of 35 vertebral segments were affected. The distribution of vertebral compression fractures included: 10 cases of L1 fracture, 12 cases of L2 fracture, 2 cases of L1+L2 fracture, 5 cases of L3 fracture, and 2 cases of L1+L3 fracture. Based on the surgical approach, patients were divided into two groups: group A (via Kambin’s triangle approach) with 15 cases, and group B (via traditional pedicle puncture) with 16 cases. Unilateral approach vertebroplasty was performed on both groups. The surgical duration, number of radiation exposures, presence of bone cement leakage, occurrence of complications such as nerve and vascular injuries were recorded in both groups. Postoperative CT scans were used to observe the dispersion and hardening of bone cement. 
RESULTS AND CONCLUSION: (1) In the group A, the surgical duration was 21-30 minutes per vertebra, with an average of (25.0±5.7) minutes. In the group B, the surgical duration was 25-43 minutes per vertebra, with an average of (33.0±7.2) minutes. The surgical duration for puncturing a single vertebra was significantly longer in the group B compared to the group A, with a statistically significant difference (P < 0.05). (2) The average number of radiation exposures per vertebra during surgery was (6.2±1.6) in the group A and (9.3±1.8) in the group B, with a statistically significant difference between the two groups (P < 0.05). (3) In the group A, no bone cement leakage was found. In group B, 2 cases had bone cement leakage, and 1 case had bone cement entering the spinal canal, but no obvious neurological symptoms were observed. The leakage rate was 13%. Both groups had 1 case of subcutaneous hematoma. (4) Postoperative CT scans for observing the distribution of bone cement in the vertebral body showed that the rates of uniform dispersion of bone cement within the vertebrae were 71% and 33% in the groups A and B, respectively, with a statistically significant difference between the two groups (P < 0.05). (5) It is suggested that percutaneous vertebroplasty via Kambin’s triangle approach offers advantages such as shorter surgical duration, better dispersion and filling of bone cement within the vertebrae, lower risk of complications, reduced radiation exposure, and satisfactory results with unilateral puncture.

Key words: osteoporotic compression fracture, Kambin’s triangle, vertebroplasty, clinical efficacy, complication, orthopedic implant, spinal implant

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