中国组织工程研究 ›› 2023, Vol. 27 ›› Issue (22): 3469-3475.doi: 10.12307/2023.367

• 骨与关节生物力学Bone and joint biomechanics • 上一篇    下一篇

有限元建模分析牵开成形治疗踝关节骨性关节炎的生物力学响应

夏煜博,唐晓霞,罗  文,徐永升,袁长飞,王  喆,周晓寒,田  苗,王  涛,郭  英   

  1. 昆明市中医医院,云南省昆明市   650500
  • 收稿日期:2022-01-06 接受日期:2022-06-13 出版日期:2023-08-08 发布日期:2022-11-02
  • 通讯作者: 王涛,硕士,主治医师,昆明市中医医院,云南省昆明市 650500 郭英,主任医师,昆明市中医医院,云南省昆明市 650500
  • 作者简介:夏煜博,男,1994年生,2021年云南中医药大学毕业,硕士,医师,主要从事中医骨伤科学方面的研究。
  • 基金资助:
    云南省科技厅科技计划项目(202001AZ070001-070),项目参与人:夏煜博

Biomechanical response of ankle traction arthroplasty for ankle osteoarthritis through finite element modeling

Xia Yubo, Tang Xiaoxia, Luo Wen, Xu Yongsheng, Yuan Changfei, Wang Zhe, Zhou Xiaohan, Tian Miao, Wang Tao, Guo Ying   

  1. Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650500, Yunnan Province, China
  • Received:2022-01-06 Accepted:2022-06-13 Online:2023-08-08 Published:2022-11-02
  • Contact: Wang Tao, Master, Attending physician, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650500, Yunnan Province, China Guo Ying, Chief physician, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650500, Yunnan Province, China
  • About author:Xia Yubo, Master, Physician, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650500, Yunnan Province, China
  • Supported by:
    the Science and Technology Planning Project of Yunnan Provincial Department of Science and Technology, No. 202001AZ070001-070 (to XYB)

摘要:


文题释义:

牵开成形术:如果关节不承受负荷,同时在间歇性流体压力变化的情况下,将改变软骨基质的代谢,从而使关节软骨得到修复,由于踝关节间隙被牵开,软骨下骨会重塑,也将有助于软骨修复。
踝关节骨性关节炎:因关节软骨创伤和退变而引发踝关节疼痛、功能障碍等的一类临床常见疾病,相关文献报道称发病率约占全身其他骨性关节炎的13%,踝关节骨性关节炎发病原因复杂多样,确切机制尚未明了,多由创伤造成踝关节内损伤。

背景:目前踝关节骨性关节炎的手术方式包括关节置换和关节融合,但2种方式均存在一定问题,因此保踝治疗成为踝关节骨性关节炎初期治疗的首选方式。牵开成形是一种重要的保踝治疗术式,有利于缓解踝关节疼痛和改善功能,有助于关节软骨的自我修复,但现在仍缺乏确切的生物力学证据。
目的:通过有限元建模探究踝关节牵开成形治疗早中期无明显力线改变的踝关节骨性关节炎的力学因素,为临床治疗提供力学证据。
方法:将1名27岁志愿者足踝CT扫描数据DICOM文件导入有限元软件中,进行三维重建及曲面拟合,再进行网格划分,建立含有骨骼、韧带、肌腱和软骨的精细足踝有限元模型,对比踝骨关节炎组、外固定架组分别在中立 0°、跖屈20°、背屈 20° 3种不同工况下的胫距关节面应力、距骨应力及距骨应变的生物力学响应。
结果与结论:①经过有限元仿真计算发现,从踝关节整体受力来说,两组模型在中立位0°时最小,从中立位逐渐跖屈或背屈时,随着踝关节活动发生变化,应力值也逐渐增加,且在同等屈曲的条件下,背屈要比跖屈的整体应力增幅明显;②从胫距关节的应力峰值来说,踝骨关节炎组的胫距关节面应力峰值较正常组增幅明显,外固定架组的胫距关节面应力峰值降幅明显;③针对踝关节整体形变,踝骨关节炎组在中立位状态时整体形变增幅最大,而外固定架组整体变形降幅最大;④从距骨应力来说,踝骨关节炎组3种工况下距骨应力均有不同程度的增加,外固定架组距骨应力有所降低,尤其在中立位时降幅明显;⑤就关节距骨前移距离而言,踝骨关节炎组距骨前移距离相对正常组明显减小,外固定架组距骨前移距离增幅不明显;⑥提示经过踝关节2种模型不同工况下的有限元仿真分析,证实临床应用踝关节牵开成形能够改变踝关节骨性关节炎患者胫距关节面及距骨的机械应力,改善关节局部的力学分布,延缓踝骨性关节炎的发展。
https://orcid.org/0000-0001-5771-984X (夏煜博) 
中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

关键词: 牵开成形术, 踝关节, 骨性关节炎, 生物力学, 有限元分析

Abstract: BACKGROUND: At present, the surgical methods for ankle osteoarthritis include joint replacement and joint fusion, but both methods have certain problems. Therefore, ankle preservation therapy has become the first choice for the initial treatment of ankle osteoarthritis. Ankle distraction arthroplasty is an important ankle-preserving procedure, which is beneficial to relieve ankle pain and improve function, and contribute to the self-repair of articular cartilage, but there is still a lack of definite biomechanical evidence.  
OBJECTIVE: To explore the mechanical factors of ankle osteoarthritis without obvious force line change in the early and middle periods using ankle distraction arthroplasty through the finite element modeling to provide mechanical evidence for clinical treatment.
METHODS: The DICOM file of CT scan data of the foot and ankle of a 27-year-old volunteer was imported into the finite element software for three-dimensional reconstruction and curved surface fitting. The mesh was divided to establish a fine foot and ankle finite element model with bones, ligaments, tendons and cartilage. The biomechanical responses of tibiotalar joint surface stress, talus stress, and talus strain under three different working conditions of 0° neutral, 20° plantar flexion, and 20° dorsiflexion were compared between the ankle osteoarthritis and external fixator groups.  
RESULTS AND CONCLUSION: (1) Through the finite element simulation calculation, it was found that the overall stress of the ankle joint was smallest in the two groups of models when the neutral position was 0°. When the neutral position was gradually flexion or dorsiflexion, the stress value gradually increased with the change of ankle joint activity. Under the same flexion condition, the overall stress of dorsiflexion was significantly greater than that of the plantar flexion. (2) In terms of the peak stress of the tibiotalar ankle joint, the peak value of the stress of the talar joint surface in the ankle osteoarthritis group increased significantly than that in the normal group, and the peak value of the stress of the tibiotalar joint surface in the external fixator group decreased significantly. (3) For the overall deformation of the ankle joint, the overall deformation of the ankle osteoarthritis group increased the most in the neutral position, while the overall deformation of the external fixator group decreased the most. (4) For the talar stress, the stress of the talus in the ankle osteoarthritis group increased in different degrees under three working conditions. The stress of the talus in the external fixator group decreased, especially in the neutral position. (5) In terms of the forward distance of the talus, the forward distance of the talus in the ankle osteoarthritis group decreased significantly compared with that in the normal group, while the forward distance of the talus in the external fixator group did not increase significantly. (6) It is concluded that through the finite element simulation analysis of two groups of ankle models under different working conditions, it is confirmed that the clinical application of ankle distraction arthroplasty can alter the mechanical stress of tibiotalar joint surface and talus in patients with ankle osteoarthritis, improve the mechanical distribution of the local joints, and delay the development of ankle osteoarthritis.

Key words: traction arthroplasty, ankle, osteoarthritis, biomechanics, finite element analysis

中图分类号: