[1] VINA ER, KWOH CK. Epidemiology of osteoarthritis: literature update. Curr Opin Rheumatol. 2018;30(2):160-167.
[2] LATOURTE A, KLOPPENBURG M, RICHETTE P. Emerging pharmaceutical therapies for osteoarthritis. Nat Rev Rheumatol. 2020;16(12):673-688.
[3] 李辉明,魏国俊,丁玉芬,等.膝关节关节腔内药物注射治疗KOA的进展[J].实用中西医结合临床,2020,20(7):157-158.
[4] 李珍一, 杨关林, 闫承慧, 等. 黄芪多糖应用的相关研究进展[J]. 辽宁中医杂志,2016,43(7):1553-1555.
[5] XIONG J, JIANG B, LUO Y, et al. Multifunctional Nanoparticles Encapsulating Astragalus Polysaccharide and Gold Nanorods in Combination with Focused Ultrasound for the Treatment of Breast Cancer. Int J Nanomed. 2020;15(10):4151-4169.
[6] 袁普卫, 杨威, 康武林,等. 骨性关节炎发病机制研究进展[J]. 中国骨质疏松杂志,2016,22(7):902-906.
[7] 胡爱心, 陈廖斌, 汪晖,等. 黄芪多糖对大鼠骨关节炎的影响[J]. 武汉大学学报(医学版),2008,29(2):157-161.
[8] CHOI MC, JO J, PARK J, et al. NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction. Cells. 2019;8(7):734-738.
[9] 李胜陶. 黄芪多糖对异丙肾上腺素诱导大鼠心肌肥厚中TLR4/NF-κB信号通路的影响[D]. 锦州:辽宁医学院,2015.
[10] PANICKER S, BORGIA J, FHIED C, et al. Oral glucosamine modulates the response of the liver and lymphocytes of the mesenteric lymph nodes in a papain-induced model of joint damage and repair. Osteoarthritis Cartilage. 2009;17(8):1014-1021.
[11] 胡爱心,陈廖斌,汪晖,等.黄芪多糖对大鼠骨关节炎的影响[J].武汉大学学报(医学版),2008,29(2):157-161.
[12] MANKIN HJ, LIPPIELLO L. Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. J Bone Joint Surg Am. 1970;52(3):424-434.
[13] GLASSON SS, CHAMBERS MG, VAN DEN BERG WB, et al. The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse. Osteoarthritis Cartilage. 2010;18(3):17-23.
[14] ABRAMOFF B, CALDERA FE. Osteoarthritis: Pathology, Diagnosis, and Treatment Options. Med Clin North Am. 2020;104(2):293-311.
[15] WANG XX, CAI L. Expression level of proteoglycan, collagen and type II collagen in osteoarthritis rat model is promoted and degradation of cartilage is prevented by glucosamine methyl ester. Eur Rev Med Pharmacol Sci. 2018;22(11):3609-3616.
[16] MALEK S, WENG HY, MARTINSON SA, et al. Evaluation of serum MMP-2 and MMP-3, synovial fluid IL-8, MCP-1, and KC concentrations as biomarkers of stifle osteoarthritis associated with naturally occurring cranial cruciate ligament rupture in dogs. PLoS One. 2020;15(11):125-129.
[17] WOODELL-MAY JE, SOMMERFELD SD. Role of Inflammation and the Immune System in the Progression of Osteoarthritis. J Orthop Res. 2020;38(2):253-257.
[18] ORHAN C, JUTURU V, SAHIN E, et al. Undenatured Type II Collagen Ameliorates Inflammatory Responses and Articular Cartilage Damage in the Rat Model of Osteoarthritis. Front Vet Sci. 2021;8(12):6-10.
[19] FEI J, LIANG B, JIANG C, et al. Luteolin inhibits IL-1β-induced inflammation in rat chondrocytes and attenuates osteoarthritis progression in a rat model. Biomed Pharmacother. 2019;109(21):1586-1592.
[20] ANSARI MY, AHMAD N, HAQQI TM. Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols. Biomed Pharmacother. 2020;129:110452.
[21] 陈瑜, 王锐卿, 刘敬萱, 等. 艾灸对膝骨关节炎患者炎性因子及氧化应激因子的影响:随机对照研究[J]. 中国针灸,2020,384(9):5-9.
[22] 王淳, 吴丽, 刘畅, 等. 利湿活血方及其拆方减轻高尿酸血症大鼠氧化应激损伤的探讨及机制研究[J]. 中华中医药杂志,2018,33(1): 85-88.
[23] 刘芬之, 郭珈宜, 李峰, 等. 独活寄生汤辨证治疗膝关节骨性关节炎的临床效果及对血清和关节腔液相关炎症细胞因子的影响[J]. 中华中医药学刊,2020,38(9):75-78.
[24] WEI B, ZHANG Y, TANG L, et al. Protective effects of quercetin against inflammation and oxidative stress in a rabbit model of knee osteoarthritis. Drug Dev Res. 2019;80(3):360-367.
[25] 刘洋, 杜婧, 沈颜红. 10种药用黄芪属植物化学成分及药理作用的研究进展[J]. 中国实验方剂学杂志,2017,23(18):222-234.
[26] 韩亚琨,于程程.黄芪多糖对实验性牙周炎骨吸收的影响[J]. 中草药,2019,50(2):423-427.
[27] 申冬冬,袁飞,侯江红. 黄芪多糖对幼鼠肠缺血再灌注损伤肠组织TNF-α、ICAM-1、IL-6及免疫功能的影响[J]. 中华中医药学刊, 2017,35(6):1528-1532.
[28] 杨彬, 黄俊卿, 张继伟. 黄芪多糖对颈椎病模型大鼠颈椎间盘纤维环MMP2和MMP9表达的影响[J]. 中国病理生理杂志,2018, 34(10):156-163.
[29] DING Y, WANG L, ZHAO Q, et al. MicroRNA93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NFκB signaling pathway. Int J Mol Med. 2019;43(2):779-790.
[30] 庄宁彤,赵冬久,史丽云. Toll样受体4(TLR4)的内吞通路及其调控机制研究进展[J]. 细胞与分子免疫学杂志,2016,32(11):1574-1578.
[31] HUANG X, QIAO F, XUE P. The protective role of microRNA-140-5p in synovial injury of rats with knee osteoarthritis via inactivating the TLR4/Myd88/NF-κB signaling pathway. Cell Cycle. 2019;18(18):2344-2358.
[32] ZHANG Y, ZENG Y. Curcumin reduces inflammation in knee osteoarthritis rats through blocking TLR4 /MyD88/NF-κB signal pathway. Drug Dev Res. 2019;80(3):353-359.
[33] LI Z, ZOU Y, FAN D, et al. The mechanism of medial collateral ligament repair in knee osteoarthritis based on the TLR4/MyD88/NF-κB inflammatory signaling pathway. J Musculoskelet Neuronal Interact. 2020;20(3):398-403.
[34] BARRETO G, SENTURK B, COLOMBO L, et al. Lumican is upregulated in osteoarthritis and contributes to TLR4-induced pro-inflammatory activation of cartilage degradation and macrophage polarization. Osteoarthritis Cartilage. 2020;28(1):92-101.
[35] ZHANG X. STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway. Cell Death Dis. 2021;12(1):13-17.
[36] WANG XZ, DING DF, XUE Y, et al. Role of TLR4/NF-κB pathway for early change of synovial membrane in knee osteoarthritis rats. Zhongguo Gu Shang. 2019;32(1):68-71.
[37] 蔡松涛, 孙京涛, 魏瑄. 枸杞多糖抑制核因子κB(NF-κB)通路降低骨关节炎软骨细胞炎性细胞因子水平[J]. 细胞与分子免疫学杂志, 2018,34(11):989-993.
[38] 陈俊, 林洁, 赵忠胜, 等. 乌头汤对膝骨关节炎模型大鼠滑膜组织TLR4/NF-κB信号通路的影响[J]. 中国组织工程研究,2019,23(27): 4381-4386.
[39] 吴佳, 尧雪洲. 在慢阻肺炎症反应中黄芪多糖的抗炎作用及抑制TLR4/NF-κB通路的机制[J]. 西安交通大学学报(医学版),2018, 39(5):760-764. |