中国组织工程研究 ›› 2022, Vol. 26 ›› Issue (35): 5724-5732.doi: 10.12307/2022.938

• 组织构建综述 tissue construction review • 上一篇    下一篇

眼动技术对自闭症患者认知行为学研究的可视化分析

佘  建1,赵  静1,张家铭1,夏海莎1,钟冬灵1,李雨谿1,郑  重2,李  涓1,金荣疆1   

  1. 1成都中医药大学养生康复学院,四川省成都市  610075;2四川大学华西医院,四川省成都市  610044
  • 收稿日期:2022-01-04 接受日期:2022-01-17 出版日期:2022-12-18 发布日期:2022-05-18
  • 通讯作者: 金荣疆,博士,教授,博士生导师,成都中医药大学养生康复学院,四川省成都市 610075
  • 作者简介:佘建,男,1997年生,汉族,四川省成都市人,成都中医药大学养生康复学院在读硕士。
  • 基金资助:
    国家自然科学基金(81873354),项目负责人:郑重;四川省科技计划(2020YFS0284),项目负责人:郑重;国家重点研发计划(2019YFC1710302),项目负责人:金荣疆

Visualization analysis of literature on eye tracking in cognitive behaviors of autistic patients

She Jian1, Zhao Jing1, Zhang Jiaming1, Xia Haisha1, Zhong Dongling1, Li Yuxi1, Zheng Zhong2, Li Juan1, Jin Rongjiang1   

  1. 1School of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, China; 2West China Hospital, Sichuan University, Chengdu 610044, Sichuan Province, China
  • Received:2022-01-04 Accepted:2022-01-17 Online:2022-12-18 Published:2022-05-18
  • Contact: Jin Rongjiang, MD, Professor, Doctoral supervisor, School of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, China
  • About author:She Jian, Master candidate, School of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, China
  • Supported by:
    the National Natural Science Foundation of China, No. 81873354 (to ZZ); Sichuan Provincial Science and Technology Plan, No. 2020YFS0284 (to ZZ); the National Key Research and Development Program of China, No. 2019YFC1710302 (to JRJ)

摘要:

文题释义:
眼动技术:是专门记录个体眼动轨迹的技术,其原理主要是通过提取个体的诸如注视点、注视时间和次数、眼跳距离及瞳孔大小等数据,从而研究个体的内在心理认知过程。
文献计量学:是指运用数学和统计学的方法对文献等知识载体进行数量分析,以反映知识发展规律和研究动态的交叉科学。

背景:眼动技术因其能客观及时且无创地反映自闭症患者的眼球运动和注意特征,较好地弥补了传统测量方法缺乏的客观性,得到了中国学者的关注,目前尚无针对眼动技术研究自闭症患者的可视化分析。
目的:利用文献计量学方法对自闭症眼动研究的相关中英文文献进行可视化分析,了解中国和国际上该领域的研究概况、热点及趋势。
方法:检索Web of Science核心合集数据库、中国知网数据库中收录的自闭症患者眼动研究的相关文献,检索时间跨度为各数据库建库至2021-11-05,使用CiteSpace(R5.8.R1)软件对文献中的关键节点信息开展文献计量及可视化分析。主要观察指标为节点的中心度、共现频次或共被引频次以及突现时间等。
结果与结论:Web of Science核心合集数据库共纳入1 458篇文献,首篇文献发表在1994年,中国知网数据库共纳入210篇文献,首篇文献发表在2007年。①国际发文量最多的作者是来自英国伦敦大学伯克贝克学院大脑与认知发展中心的JOHNSON MH,发文量最多的机构是伦敦大学学院。②中国发文量最多的作者是来自闽南师范大学应用心理研究所的陈顺森,发文量最多的机构是闽南师范大学应用心理研究所。③国际与中国研究热点存在一定差异,中国研究学者多集中于儿童自闭症患者对外部社会性线索的注意偏向行为模式的研究,研究成果主要是自闭症儿童存在负性情绪线索注意偏向和眼部注意偏向;国际研究学者不仅聚焦于儿童及婴幼儿自闭症患者处理社会性线索视觉模式,同时还结合脑影像技术研究引起视觉行为模式异常的潜在神经机制,研究成果主要是自闭症患者的异常注意模式主要与杏仁核、枕颞叶以及梭状回等相关脑区的激活程度相关。④未来研究学者们还需进一步探索与自闭症有关的生物标志物,为自闭症患者的早期诊断及干预提供生物预测模型。

https://orcid.org/0000-0002-4733-9955(金荣疆);https://orcid.org/0000-0002-4979-1275(佘建) 

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松;组织工程

关键词: 自闭症谱系障碍, CiteSpace, 眼动研究, 可视化分析, 认知行为模式, 神经机制, 婴幼儿, 儿童

Abstract: BACKGROUND: Eye tracking has attracted the attention of Chinese scholars because it can objectively, timely and non-invasively reflect the eye movement and attention characteristics of autistic patients, which makes up for the lack of objectivity of traditional measurement methods. However, there is yet no visualization analysis of literature on eye tracking in autistic patients.
OBJECTIVE: To perform the visualization analysis of relevant Chinese and English literature on eye tracking in autism and to understand the research overview, hot spots and trends in this field. 
METHODS: Literature related to eye tracking in autistic patients were searched in Web of Science Core Collection database and CNKI database from their inception to November 5, 2021. Bibliometrics and visualization analysis of key node information in the literature was conducted using CiteSpace software (R5.8.R1). The main observation indexes were node centrality, co-occurrence frequency or co-citation frequency, and burst time.
RESULTS AND CONCLUSION: A total of 1 458 papers were included in the Web of Science core Collection database, the first of which was published in 1994, and 210 papers were included in the CNKI database, the first of which was published in 2007. The international author with the most publications is JOHNSON MH who is from the Centre for Brain and Cognitive Development, Birkbeck, University of London, and the institution with the most publications is University College London. In China, Chen Shunsen who is from the Institute of Applied Psychology of Minnan Normal University has published the most papers, and the institution with the most publications is the Institute of Applied Psychology of Minnan Normal University. There are some differences between domestic and international research hotspots. Domestic researchers mostly focus on the attentional bias behavior pattern of children with autism towards external social cues, and their results mainly show that children with autism have attentional bias of negative emotional cues and eye attention bias. International researchers not only focus on the visual patterns of processing social cues in children and infants with autism, but also use brain imaging technology to study the underlying neural mechanisms of abnormal visual behavior patterns. The main research results are that the abnormal attention pattern of autism patients is mainly related to the activation of amygdala, occipito-temporal lobe and fusiform gyrus. Further research on biomarkers related to autism is required to provide objective indicators for early diagnosis and intervention of autistic patients.

Key words: autism spectrum disorder, CiteSpace, eye tracking, visualization analysis, cognitive behavior pattern, neuromechanism, infant, children

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