中国组织工程研究 ›› 2021, Vol. 25 ›› Issue (27): 4354-4360.doi: 10.12307/2021.196

• 骨科植入物 orthopedic implant • 上一篇    下一篇

经皮空心加压螺钉联合内侧支撑钢板置入治疗青壮年改良Pauwels Ⅲ型股骨颈骨折的2年随访

任思俊,曹志鹏,徐  饶,茹江英   

  1. 扬州大学附属医院,江苏省扬州市   225000
  • 收稿日期:2020-11-28 修回日期:2020-12-04 接受日期:2020-12-31 出版日期:2021-09-28 发布日期:2021-04-10
  • 通讯作者: 茹江英,博士,主任医师,副教授,硕士生导师,扬州大学附属医院骨科,江苏省扬州市 225000
  • 作者简介:任思俊,男,1994年生,安徽省宿州市人,扬州大学医学院在读硕士,主要从事创伤与骨关节损伤研究。
  • 基金资助:
    江苏省卫生计生委科研课题面上项目(H201662),项目负责人:茹江英;扬州市重点研发(社会发展)项目(YZ2018086),项目负责人:茹江英

Fixation of the modified Pauwels type Ⅲ femoral neck fractures in young adults with percutaneous hollow compression screw combined with medial buttress plate: 2-year follow-up

Ren Sijun, Cao Zhipeng, Xu Rao, Ru Jiangying   

  1. Affiliated Hospital of Yangzhou University, Yangzhou 225000, Jiangsu Province, China
  • Received:2020-11-28 Revised:2020-12-04 Accepted:2020-12-31 Online:2021-09-28 Published:2021-04-10
  • Contact: Ru Jiangying, MD, Chief physician, Associate professor, Master’s supervisor, Affiliated Hospital of Yangzhou University, Yangzhou 225000, Jiangsu Province, China
  • About author:Ren Sijun, Master candidate, Affiliated Hospital of Yangzhou University, Yangzhou 225000, Jiangsu Province, China
  • Supported by:
    the Scientific Research Project of Jiangsu Provincial Health and Family Planning Commission, No. H201662 (to RJY); the Key Research and Development (Social Development) Funding Project of Yangzhou City, No. YZ2018086 (to RJY)

摘要:

文题释义:
Pauwels Ⅲ型股骨颈骨折:即垂直剪切型股骨颈骨折,具有创伤能量较高、骨折端剪切应力较大、粉碎性骨块较多、移位较明显和血运的破坏较大等特点,术后较易发生内固定失败、骨折不愈合及股骨头无菌性坏死等并发症。
直接前侧入路:即Hueter间隙入路,由阔筋膜张肌与股直肌的间隙进入,是真正的神经肌肉间隙入路。在切开复位股骨颈骨折中的优势在于:①创伤较小,出血少,术后疼痛轻,康复快,住院时间短;②可获得满意的解剖复位,避免旋股内侧动脉的损伤及降低股骨头无菌性坏死发生的概率;③有利于在股骨颈前内下方置入内侧支撑钢板,增加骨折固定的稳定性。
经皮空心加压螺钉联合内侧支撑钢板内固定:此次研究采用在3枚经皮空心加压螺钉固定基础上附加内侧支撑钢板,1/3管型钢板作支撑钢板跨骨折线置于股骨颈前内下方“安全区”,能够增加骨折断端抗垂直剪切应力和轴向压应力,从而提高内固定的力学稳定性。

背景:尽管内固定材料和技术不断改进和完善,但对于青壮年Pauwels Ⅲ型股骨颈骨折的治疗仍面临较大的挑战和争议。
目的:探讨经皮空心加压螺钉联合直接前侧入路附加内侧支撑钢板内固定治疗青壮年改良Pauwels Ⅲ型股骨颈骨折的早期疗效、主要并发症发生的原因及围术期需要注意的问题。
方法:回顾性分析2016年11月至2018年11月扬州大学附属医院收治的18例采用经皮空心加压螺钉联合直接前侧入路附加内侧支撑钢板内固定治疗的青壮年改良Pauwels Ⅲ型股骨颈骨折患者的临床资料。记录受伤至入院时间、受伤到手术时间、手术时间、术后部分负重时间及完全负重时间、影像骨愈合时间和临床骨愈合时间;根据X射线片和CT检查结果判断术后内固定失效、骨折不愈合、股骨颈短缩及股骨头无菌性坏死发生情况,对疑有股骨头坏死者进一步行MRI检查;同时在术后即刻、术后3,6,12,24个月随访时,通过Harris 评分、Garden对线指数对患髋术后的功能恢复状况和复位质量进行评估。
结果与结论:①18例患者均获得随访,随访时间24-36个月;平均影像骨愈合时间和临床骨愈合时间分别为(4.3±1.1)个月(3.8-6.1个月)和(5.8±0.9)个月(4.9-8.2 个月);②在患髋正、侧位X射线片上评估Garden 对线指数,术后即刻、术后3,6,12,24个月不同时间点之间两两比较差异均无显著性意义(P > 0.05);③术后3,6,12,24个月,患髋的各项Harris评分及总分均显著高于术前(P < 0.05);术后6,12,24个月,患髋的各项Harris评分及总分与术后3个月相比均显著改善(P < 0.05);与术后6个月相比,术后12,24个月的患髋功能、活动范围及总分均显著改善(P < 0.05);④所有患者伤口一级愈合,无骨折不愈合、下肢深静脉血栓、坠积性肺炎、压疮等并发症发生;2例患者术后发生空心加压螺钉退出伴股骨颈短缩(约8 mm),但最终顺利完成临床骨愈合;1例患者术后2年随访时发生股骨头无菌性坏死伴塌陷,随后行直接前侧入路人工全髋关节置换予以翻修;1例患者髋关节过度屈曲时出现明显疼痛,术后3个月症状缓解;⑤结果表明,采用经皮空心加压螺钉联合直接前侧入路附加内侧支撑钢板内固定治疗青壮年改良Pauwels Ⅲ型股骨颈骨折,可直视下完成骨折端的解剖复位,固定可靠,术后早期疗效令人满意,但需严格手术指征和加强围术期管理,积极预防主要并发症如骨折不愈合和股骨头无菌性坏死的发生。
https://orcid.org/0000-0003-4217-1468 (任思俊) 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

关键词: 股骨颈骨折, 改良Pauwels Ⅲ型, 青壮年, 直接前方入路, 空心加压螺钉, 内侧支撑钢板, 并发症

Abstract: BACKGROUND: Although materials and technologies of internal fixation have been improved significantly, the treatment of Pauwels III fractures of femoral neck in young adults remains a challenging and controversial issue.  
OBJECTIVE: To explore the early effect of percutaneous hollow compression screw combined with medial buttress plate via direct anterior approach for modified Pauwels type III femoral neck fractures in young adults, causes of main complications and problems in perioperative period need to be paid attention to.
METHODS:  Clinical data of 18 young adults of modified Pauwels type III femoral neck fractures in young adults treated with percutaneous hollow compression screw combined with medial buttress plate via direct anterior approach in Affiliated Hospital of Yangzhou University from November 2016 to November 2018 were retrospectively analyzed in this retrospective study. The data, including time from injury to admission, time from injury to operation, operation time, postoperative partial-weight bearing time and full-weight bearing time, imaging bone healing time and clinical bone healing time, were all required to be carefully recorded. According to the results of X-ray and CT examination, the failure of internal fixation, bone non-unions, femoral neck shortening, and aseptic necrosis of the femoral head were assessed. It was necessary to further perform MRI if having suspected the occurrence of aseptic necrosis of the femoral head. Meanwhile, the reduction quality and functional recovery of the affected hips, at immediately, 3, 6, 12, and 24 months after surgery, were evaluated respectively by Garden's alignment index and the Harris score.  
RESULTS AND CONCLUSION: (1) In all 18 patients, the average follow-up time was 24-36 months. The average image bone healing time and clinical bone healing time were (4.3±1.1) months (3.8-6.1 months) and (5.8±0.9) months (4.9-8.2 months), respectively. (2) There was no significant difference in Garden’s alignment index on the anteroposterior and lateral X-rays of the affected hip immediately, 3, 6, 12, and 24 months after surgery (P > 0.05). (3) At 3, 6, 12, and 24 months after surgery, the Harris scores and total scores of the affected hip were all significantly higher than those before surgery (P < 0.05). Compared with 3 months after surgery, the Harris scores and total scores of the affected hip were all significantly improved at 6, 12, and 24 months after surgery (P < 0.05). Compared with 6 months after surgery, the hip function, range of motion and total Harris score were all significantly improved at 12 and 24 months after surgery (P < 0.05). (4) The wounds of all patients healed at the first level, and there were no complications such as nonunion, deep venous thrombosis, hypostatic pneumonia, or bed sore. Two cases of patients had withdrawals of hollow compression screw accompanied with shortening of the femoral neck after surgery (about 8 mm), but the clinical bone healing was successfully completed. Aseptic necrosis of the femoral head occurred in one patient concomitant with hip dysfunction 2 years postoperatively, who was revised subsequently by total hip arthroplasty via original direct anterior approach. One patient experienced obvious pain during the hyperflexion of the hip joint, and the symptoms were relieved 3 months after the primary operation without special treatment. 
(5) The all outcomes indicated that fixation of percutaneous hollow compression screw combined with medial buttress plate via direct anterior approach in young adults with modified Pauwels type III femoral neck fractures can achieve the anatomical reduction and fixation of the fractures under direct vision, and its early effect is satisfactory. However, it is required to control surgical indications and strengthen perioperative management strictly so as to prevent the occurrence of major complications, such as nonunion and aseptic necrosis of the femoral head.

Key words: femoral neck fracture, modified Pauwels type III, young adults, direct anterior approach, hollow compression screw, medial buttress plate, complications

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